Surgery for Melanoma

For most people with melanoma, surgery is the first and main treatment — and often the only one needed when the melanoma is caught early. This page explains what melanoma surgery involves, from removing the melanoma itself to skin grafts and recovery.

In some cases, an excision biopsy will have removed the melanoma entirely. Depending on the stage, size and depth of the melanoma, a wide local excision may be recommended, which involves removing a larger area of skin around the melanoma. The amount of tissue removed depends on the position and depth of the melanoma, and whether the surgery will affect your movement afterwards.48

The type of surgery you’re offered often depends on the stage of your melanoma — you can read more about this in our guide to melanoma treatment by stage. Read on below for more detail on how a wide local excision takes place, along with sentinel lymph node biopsy, skin grafts and skin flaps.

You may want to ask your doctor these questions about surgery:

  • What surgery do you recommend for me? Why?
  • What is involved in the surgery?
  • Do I need to stay in the hospital?
  • Will I have pain after the surgery? How will you manage my pain?
  • What problems do I need to watch for after surgery?
  • Will there be a scar?
  • Are there any long-term side effects?

More About Melanoma Surgery

Before your surgery

Before surgery, your specialist will carry out a physical examination of your lymph nodes to check whether the melanoma has spread to them. This is because the most common place for melanoma cells to spread is to the lymph nodes closest to the melanoma.

Your specialist will check whether they look or feel swollen. If the melanoma is on your leg, they’ll examine the lymph nodes behind your knee and in your groin. If it’s on your chest, back or abdomen, they’ll check the lymph nodes in your groin, armpits, above the collarbones and in the neck.

If any of these lymph nodes are obviously swollen, your specialist will suggest further tests to check them. Early-stage melanomas rarely spread to the lymph nodes.

Wide local excision

Surgery to remove a larger area of healthy skin from around where the melanoma was is known as a wide local excision. How much skin is removed depends on whether any melanoma cells might have been left behind in the surrounding skin, how deep the melanoma is, and its position on the body.

You may have the wide local excision under a local anaesthetic in the day surgery unit. The doctor will put in stitches to close up the area where they remove the skin. This can feel a little tight at first, but as it heals the surrounding skin will stretch and the tightness should ease.

Sentinel lymph node biopsy

If your melanoma is deeper than 1mm (stage 1B to 2C), you might be offered a sentinel lymph node biopsy. This is a test to find the first lymph node or nodes that a melanoma may spread to, and then check for the presence of cancer cells. You would have a sentinel lymph node biopsy at the same time as your operation to remove the melanoma.

Skin grafts56

Sometimes, if your doctor needs to remove a large area of skin, you might have a skin graft to help repair it. A skin graft is a layer of skin taken from another part of the body and placed over the area where the melanoma was removed. The place where the skin is taken from is known as the donor site, and the place it is moved to is called the grafted area. The amount of skin taken depends on the area to be covered. Your doctor or specialist nurse will tell you more about this.

The grafted area

The grafted area may be secured with stitches. You’ll have a dressing over it, which will be left in place while the graft heals. The skin graft will connect with the blood supply in the area — this usually takes 5–7 days. It will look red and swollen to begin with, but eventually it will heal and the redness will fade.

The donor site

You will have a dressing on the donor site to protect it from infection. How long it takes to heal depends on how much skin was removed. If skin was taken from the thigh, buttock or upper arm, it may take up to two weeks to heal. If it was taken from the neck, behind the ears or the inner side of the upper arm, it may take only about five days. The donor site can often feel more uncomfortable than the grafted area, and you may need to take regular painkillers for a while.

After skin graft surgery

After a skin graft, it is usually possible to go home on the same day.

Try not to do too much during the first couple of weeks after your skin graft — you’ll need to allow the graft to heal properly. The grafted area will be quite fragile, so it’s important not to put pressure on it, or rub or brush against it. Some people may need to take time off work until it’s healed. If you have children, you may need some extra help at home until you feel able to do the things you normally do.

Your stitches will be removed 5–14 days after your operation. Some people may have stitches that dissolve and don’t need to be removed. Both the grafted and donor areas will develop scars, which should gradually become less noticeable over time. There will also be some difference between the grafted skin and the skin surrounding it, which will lessen over time. Your hospital team can tell you more about what to expect.

Skin flaps

A skin flap is a slightly thicker layer of skin than a graft. It is taken from an area very close to where the melanoma was. The flap is cut away but left partially connected so it still has a blood supply, then moved over the wound and stitched in place. If you have a skin flap, you may need to stay in hospital for up to four days.

Skin flap surgery is very specialised and is usually done by a plastic surgeon. If you need a skin flap, your doctor will be able to tell you more about it.

After your surgery, your care continues with follow-up appointments to monitor your recovery — read more about what to expect at follow-up.

Click HERE for a full list of REFERENCES numbers listed throughout the site (nos. 1–58)

Available Treatments

Treatment By Stage

The treatment your team recommends depends heavily on the stage of your melanoma, from stage 0 through to stage 4. Our stage-by-stage guide explains what each one means and the options usually considered at each.

Targeted Therapies

Targeted therapies work on specific genetic changes inside melanoma cells — most commonly in a gene called BRAF — which is why you may be offered a BRAF test. They're an option for people whose melanoma carries these changes.

Surgery for Melanoma

For most people with melanoma, surgery is the first and main treatment — and often the only one needed when the melanoma is found early. It involves removing the melanoma along with a margin of surrounding skin, and sometimes checking nearby lymph nodes.
Stage IV Melanoma Treatment Options Decision Guide

Stage IV Melanoma Guide

This booklet is for anyone diagnosed with — or being evaluated for — stage 4 melanoma, the most advanced stage, where the melanoma has spread beyond where it started. It's designed to help you understand and weigh up your treatment options.
Second opinion from DR or Melanoma

Second Opinion

It's completely normal to want reassurance about your diagnosis or treatment plan, and you have every right to ask for a second opinion. It won't offend your medical team — it's a recognised part of your care.
radiotherapy treatment for melanoma

Radiotherapy for Melanoma

Radiotherapy uses carefully targeted radiation to treat melanoma. It isn't used as often as surgery or drug treatments, but it can play a role in certain situations, such as treating melanoma that has spread.

Other Therapies

Some less common treatments, such as isolated limb infusion (ILI) and isolated limb perfusion (ILP), may be recommended when melanoma is confined to one area, such as an arm or leg. These deliver treatment directly to the affected limb.

Learn about BRAF – watch our video

Around half of people diagnosed with melanoma have a change in their cancer cells called a BRAF V600E gene mutation. Watch our short video to understand what BRAF means and why it matters for your treatment options.

Immunotherapy

Immunotherapy works by helping your own immune system recognise and attack melanoma cells. It's often used for melanoma that has spread or has a higher risk of returning, and several immunotherapy treatments are now available on the NHS.
Removal of Melanoma

Excision

Local excision is where the abnormal mole or area of skin is removed and sent to a laboratory for testing. It's a relatively simple operation and is often the first step in diagnosing and treating melanoma.

Next Steps

Follow up appointments with your GP after Melanoma

FOLLOW UP APPOINTMENTS

Your follow-up care depends on the stage of the melanoma. Follow-up appointments allow your doctor to monitor for possible recurrence of the melanoma.
Aftercare advice to follow after Melanoma

MELANOMA AFTER CARE

It’s important to regularly check yourself for any signs of melanoma. As you have already been diagnosed with melanoma, you are at a higher than average risk of having another melanoma in the future.

MELANOMA FURTHER TESTS

If the initial biopsy shows melanoma, you may need further tests. Understanding the extent of the melanoma can help your doctor decide the best treatment option for you.

MELANOMA SKIN BIOPSY

If your doctor does find a suspicious mole, a sample of tissue is removed (a biopsy) for examination under a microscope. The doctor first numbs the skin with an injection of a local anaesthetic
Getting diagnosed for Melanoma

GETTING DIAGNOSED WITH MELANOMA

See your doctor if you develop a new mole or notice a change in an existing mole or area of your skin (including under your nail). Even if you’re worried about what this might be, you shouldn’t delay seeing them. It might not be cancer.